Medical University of South Carolina

College of Medicine & Hollings Cancer Center

Cell and Molecular Pharmacology &

Experimental Therapeutics

Allosteric Regulation of Phosphorylation based Signaling

The main focus of our laboratory is to unravel the allosteric underpinnings of Phosphorylation-based signaling. We are a basic sciences laboratory that indulges in biochemical and biophysical characterization of proteins orchestrating protein phosphorylation. Individual projects on Protein Kinases and Protein Phosphatases explore their duality as enzymes and signaling scaffolds.